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Despite regular reference to conspiracy theories as a "belief system," few studies have attempted to explore the structure and organization of conspiracy beliefs beyond an examination of correlations between those beliefs. Employing unique data from two national surveys that includes respondent beliefs in 27 conspiracy theories, we decipher the substantive dimensions along which conspiracy beliefs are organized, as well as subgroupings within those dimensions. We find that variation in these conspiracy beliefs can be accounted for with two dimensions: the first regards partisan and ideological identities, while the other is composed of anti-social orientations, such as narcissism, Machiavellianism, psychopathy, and acceptance of political violence. Importantly, these two dimensions are uncorrelated. We also find that conspiracy beliefs group together by substantive content, such as those regarding partisan actors or science/medicine. Our findings also demonstrate that inferences about the correlates of conspiracy beliefs are highly contingent on the specific conspiracy theories employed by researchers. We provide suggestions for future research in this vein.

AbstractContemporary political ills at the mass behavior level (e.g., outgroup aggression, conspiracy theories) are often attributed to increasing polarization and partisan tribalism. We theorize that many such problems are less the product of left‐right orientations than an orthogonal "anti‐establishment" dimension of opinion dominated by conspiracy, populist, and Manichean orientations. Using two national surveys from 2019 and 2020, we find that this dimension of opinion is correlated with several antisocial psychological traits, the acceptance of political violence, and time spent on extremist social media platforms. It is also related to support for populist candidates, such as Trump and Sanders, and beliefs in misinformation and conspiracy theories. While many inherently view politics as a conflict between left and right, others see it as a battle between "the people" and a corrupt establishment. Our findings demonstrate an urgent need to expand the traditional conceptualization of mass opinion beyond familiar left‐right identities and affective orientations.

Abstract
Minor intron–containing genes (MIGs) account for <2% of all human protein–coding genes and are uniquely dependent on the minor spliceosome for proper excision. Despite their low numbers, we surprisingly found a significant enrichment of MIG-encoded proteins (MIG-Ps) in protein–protein interactomes and host factors of positive-sense RNA viruses, including SARS-CoV-1, SARS-CoV-2, MERS coronavirus, and Zika virus. Similarly, we observed a significant enrichment of MIG-Ps in the interactomes and sets of host factors of negative-sense RNA viruses such as Ebola virus, influenza A virus, and the retrovirus HIV-1. We also found an enrichment of MIG-Ps in double-stranded DNA viruses such as Epstein–Barr virus, human papillomavirus, and herpes simplex viruses. In general, MIG-Ps were highly connected and placed in central positions in a network of human–host protein interactions. Moreover, MIG-Ps that interact with viral proteins were enriched with essential genes. We also provide evidence that viral proteins interact with ancestral MIGs that date back to unicellular organisms and are mainly involved in basic cellular functions such as cell cycle, cell division, and signal transduction. Our results suggest that MIG-Ps form a stable, evolutionarily conserved backbone that viruses putatively tap to invade and propagate in human host cells.